Research areas:
cardiac tissue engineering
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2022

[Pre-print; Software]
Rianú: Multi-tissue tracking software for increased throughput of engineered cardiac tissue screening
Jack F. Murphy | Kevin D. Costa | Irene C. Turnbull
Manuscript in Preparation. 2022.


2019

[Paper]
Adult human cardiac stem cell supplementation effectively increases contractile function and maturation in human engineered cardiac tissues
Jack F. Murphy | Joshua Mayourian | Francesca Stillitano | Sadek Munawar | Kathleen M. Broughton | Esperanza Agullo-Pascual | Mark A. Sussman | Roger J. Hajjar | Kevin D. Costa | Irene C. Turnbull
Stem Cell Research and Therapy 2019. PMID: 31801634.


[Abstract]
Cardiac Stem Cells from Failing Heart Improve Contractility of Engineered Human Myocardium
Jack F. Murphy | Joshua Mayourian | Francesca Stillitano | Sadek Munawar | Kathleen M. Broughton | Mark A. Sussman | Roger J. Hajjar | Kevin D. Costa | Irene C. Turnbull
Biomedical Engineering Society Annual Meeting. Philadelphia, PA. 2019.


[Abstract]
Comparison of cell culturing conditions and extracellular vesicles preservation techniques to maximize cardioactive potency of the adult stem cell secretome
Sophia I. Salazar | Joshua Mayourian | Henry Chionuna | Jack F. Murphy | Kevin D. Costa | Irene C. Turnbull
New York Academy of the Sciences 2019.


2018

[Abstract]
Adult Human Cardiac Progenitor Cells Enhance Contractile Force in Human Engineered Cardiac Tissues
Jack F. Murphy | Joshua Mayourian | Sophia I. Salazar | Delaine K. Ceholski | Venu Pothula | Francesca Stillitano | Jaydev Dave | Kathleen Broughton | Mark Sussman | Roger J. Hajjar | Kevin D. Costa | Irene C. Turnbull
AHA Scientific Sessions 2018.


[Abstract]
Heterocellular Coupling Mediates Pro-Contractile Effects Of Cardiac Progenitor Cells In Human Engineered Cardiac Tissue
Irene C. Turnbull | Jack F. Murphy | Joshua Mayourian | Sophia I. Salazar | Delaine K. Ceholski | Venu Pothula | Francesca Stillitano | Kathleen Broughton | Mark Sussman | Roger J. Hajjar | Kevin D. Costa
International Society for Stem Cell Research 2018.


[Book Chapter]
Cardiac Tissue Engineering Models of Inherited and Acquired Cardiomyopathies
Irene C. Turnbull | Joshua Mayourian | Jack F. Murphy | Francesca Stillitano | Delaine K. Ceholski | Kevin D. Costa
Methods in Molecular Biology [Book Series] 2018. PMID: 29987817.


[Paper]
Exosomal microRNA-21-5p Mediates Mesenchymal Stem Cell Paracrine Effects on Human Cardiac Tissue Contractility
Joshua Mayourian | Delaine K. Ceholski | Przemek A. Gorski | Prabhu Mathiyalagan | Jack F. Murphy | Sophia I. Salazar | Francesca Stillitano | Joshua M. Hare | Susmita Sahoo | Roger J. Hajjar | Kevin D. Costa
Circulation Research 2018. PMID: 29449318.