Jack F. Murphy

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Background

I was born and raised in New York City. While in high school I had the opportunity to conduct research in the Costa Lab at the Icahn School of Medicine at Mount Sinai. Through this experience, I developed a deep interest in the fields of tissue engineering and cardiac regeneration. I have now moved my passions over to Dublin while I pursue a degree in Biomedical Engineering from Trinity College Dublin.

During term I work in the Monaghan Lab in the Trinity Biomedical Sciences Intstitute. While, during the summer I spend my time in the Costa Lab at Mt. Sinai. 

Education

Trinity College Dublin, The University of DublinExpected: 2018-2023

BACCALAUREUS IN ARTE INGENIARIA (B.A.I) + MAGISTER IN ARTE INGENIARIA (M.A.I) IN BIOMEDICAL ENGINEERING

Recent Projects

Cardiac Tissue Engineering

Costa Lab, Icahn School of Medicine

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Jack F. Murphy

Cardiac Tissue Tracking System

A system designed to more efficiently record, track, and analyze contracting cardiac tissue strips. 

Docs

Publications

2019

Murphy, J. F., Mayourian, J., Stillitano, F.,  Munawar, S., Broughton, K. M., Agullo-Pascual, E., Sussman, M. A.,  Hajjar, R. J., Costa, K. D. & Turnbull, I. C. (2019).  Adult human cardiac stem cell supplementation effectively increases contractile function and maturation in human engineered cardiac tissues. Stem Cell Res Ther 10, 373

[Abstract] Murphy, J. F., Mayourian, J., Stillitano, F., Munawar, S., Broughton, K. M., Sussman, M. A., Hajjar, R. J., Costa, K. D. & Turnbull, I. C. (2019). Cardiac Stem Cells from Failing Heart Improve Contractility of Engineered Human Myocardium. 2019 Biomedical Engineering Society Annual Meeting. Philadelphia, PA. October 16-19, 2019

2018

[Abstract] Murphy, J. F., Mayourian, J., Salazar, S. I., Ceholski, D. K., Pothula, V. M., Stillitano, F., Dave, J., Broughton, K., Sussman, M., Hajjar, R. J., Costa, K. D. & Turnbull, I. C. (2018)  Adult Human Cardiac Progenitor Cells Enhance Contractile Force in Human Engineered Cardiac Tissues. AHA Scientific Sessions 2018. Nov 12, 2018.

[Abstract] Turnbull, I. C., Murphy, J. F., Mayourian, J., Salazar, S. I., Ceholski, D. K., Pothula, V., Stillitano, F., Broughton, K., Sussman, M., Hajjar, R. J. & Costa, K. D. (2018). Heterocellular Coupling Mediates Pro-Contractile Effects Of Cardiac Progenitor Cells In Human Engineered Cardiac Tissue. International Society for Stem Cell Research. June 2018: 52-53

Turnbull, I. C., Mayourian, J., Murphy, J. F., Stillitano, F., Ceholski, D. K. & Costa, K. D. (2018). Cardiac Tissue Engineering Models of Inherited and Acquired Cardiomyopathies. Methods Mol Biol 1816: 145-159

Mayourian, J., Ceholski, D. K., Gorski, P. A., Mathiyalagan, P., Murphy, J. F., Salazar, S. I., Stillitano, F., Hare, J. M., Sahoo, S., Hajjar, R. J. & Costa, K. D. (2018).  Exosomal microRNA-21-5p Mediates Mesenchymal Stem Cell Paracrine Effects on Human Cardiac Tissue Contractility. Circ Res 122(7): 933-944.

Other Interests

Rock Climbing

Volunteering