Jack F. Murphy

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Background

I was born and raised in New York City. While in high school I had the opportunity to conduct research in the Costa Lab at the Icahn School of Medicine at Mount Sinai. Through this experience, I developed a deep interest in the fields of tissue engineering and cardiac regeneration. I have now moved my passions over to Dublin while I pursue a degree in Biomedical Engineering from Trinity College Dublin.

During term I work in the Monaghan Lab in the Trinity Biomedical Sciences Institute. During the summer I spend my time in the Costa Lab at Mt. Sinai. 

Education

Trinity College Dublin, The University of DublinExpected: 2018-2023

BACCALAUREUS IN ARTE INGENIARIA (B.A.I) + MAGISTER IN ARTE INGENIARIA (M.A.I) IN BIOMEDICAL ENGINEERING

Recent Projects

Cardiac Tissue Engineering

Costa Lab, Icahn School of Medicine

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Jack F. Murphy

Cardiac Tissue Tracking System

A system designed to more efficiently record, track, and analyze contracting cardiac tissue strips. 

Docs

Publications

[Updated daily from Google Scholar]

2019

Murphy, J. F., Mayourian, J., Stillitano, F.,  Munawar, S., Broughton, K. M., Agullo-Pascual, E., Sussman, M. A.,  Hajjar, R. J., Costa, K. D. & Turnbull, I. C. (2019).  Adult human cardiac stem cell supplementation effectively increases contractile function and maturation in human engineered cardiac tissues. Stem Cell Res Ther 10, 373.

[Abstract] Murphy, J. F., Mayourian, J., Stillitano, F., Munawar, S., Broughton, K. M., Sussman, M. A., Hajjar, R. J., Costa, K. D. & Turnbull, I. C. (2019). Cardiac Stem Cells from Failing Heart Improve Contractility of Engineered Human Myocardium. 2019 Biomedical Engineering Society Annual Meeting. Philadelphia, PA. October 16-19, 2019.

[Abstract] Salazar, S. I., Mayourian, J., Chionuna, H., Murphy, J. F., Costa, K. D. & Turnbull, I. C. (2019). Comparison of cell culturing conditions and extracellular vesicles preservation techniques to maximize cardioactive potency of the adult stem cell secretome. Extracellular Vesicles in Diagnostics and Therapeutics Symposium. New York Academy of the Sciences. February 19, 2019. 

2018

[Abstract] Murphy, J. F., Mayourian, J., Salazar, S. I., Ceholski, D. K., Pothula, V. M., Stillitano, F., Dave, J., Broughton, K., Sussman, M., Hajjar, R. J., Costa, K. D. & Turnbull, I. C. (2018)  Adult Human Cardiac Progenitor Cells Enhance Contractile Force in Human Engineered Cardiac Tissues. AHA Scientific Sessions 2018. Nov 12, 2018.

[Abstract] Turnbull, I. C., Murphy, J. F., Mayourian, J., Salazar, S. I., Ceholski, D. K., Pothula, V., Stillitano, F., Broughton, K., Sussman, M., Hajjar, R. J. & Costa, K. D. (2018). Heterocellular Coupling Mediates Pro-Contractile Effects Of Cardiac Progenitor Cells In Human Engineered Cardiac Tissue. International Society for Stem Cell Research June 2018: 52-53.

Turnbull, I. C., Mayourian, J., Murphy, J. F., Stillitano, F., Ceholski, D. K. & Costa, K. D. (2018). Cardiac Tissue Engineering Models of Inherited and Acquired Cardiomyopathies. Methods Mol Biol 1816: 145-159.

Mayourian, J., Ceholski, D. K., Gorski, P. A., Mathiyalagan, P., Murphy, J. F., Salazar, S. I., Stillitano, F., Hare, J. M., Sahoo, S., Hajjar, R. J. & Costa, K. D. (2018).  Exosomal microRNA-21-5p Mediates Mesenchymal Stem Cell Paracrine Effects on Human Cardiac Tissue Contractility. Circ Res 122(7): 933-944.

Other Interests

Rock Climbing

Volunteering